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Tesamorelin 5mg

$69.99

Boost your wellness and support healthy body composition with Sana Tesamorelin, available in two convenient variations: 5โ€ฏmg. Lab-tested, pure, and effective.

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Tesamorelin is a synthetic growth hormoneโ€“releasing hormone (GHRH) analogue used as a laboratory tool compound to investigate growth hormoneโ€“releasing hormone receptor (GHRHR) signaling and downstream endocrine pathway dynamics in preclinical experimental systems. The molecule incorporates an additional trans-3-hexanoic acid group, a peptide-chemistry modification often used to modulate physicochemical stability and proteolytic susceptibility in biological matrices. In RUO settings, tesamorelin is applied in mechanistic studies of receptor-coupled signaling, endocrine feedback circuitry, and GH/IGF-axisโ€“associated molecular readouts in controlled in-vitro assays and in-vivo animal models.

Tesamorelin Structure

Sequence (Single Letter):ย Unk-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu
Molecular Formula:ย C223H370N72O69S
Molecular Weight:ย 5195.908 g/mol
PubChem CID:ย 44147413
CAS Number:ย 901758-09-6

Tesamorelin Research

As a GHRH analogue, tesamorelin is used in laboratory research to probe GHRHR activation and downstream signaling associated with GH/IGF-axis regulation. In experimental contexts, GHRHR engagement is commonly associated with GPCR-mediated signaling (often Gs/cAMP-linked), modulation of kinase activity, and transcriptional programs that influence endocrine signaling dynamics. The trans-3-hexanoic acid modification is used in peptide engineering to support reproducible exposure profiles in controlled research workflows and to facilitate mechanistic interrogation of receptor signaling and feedback regulation.

Experimental Modeling of Visceral Adiposity & Lipid Biomarkers

Published studies have evaluated tesamorelin and related growth hormoneโ€“releasing factor analogues in research cohorts using metabolic endpoints and biomarker readouts. Reported analyses include associations between changes in visceral adipose tissue measures and lipid parameters such as triglyceridesย [3], [4]. These citations are provided strictly for scientific background and do not imply any intended medical, diagnostic, or therapeutic use.

Figure included as an educational reference to the cited publication record.
Source:ย PubMed

Endocrine Axis Research in Chronic Infection Models

Reviews and mechanistic discussions have described endocrine and metabolic alterations observed in chronic infection research settings, including reported changes in growth hormone axis parametersย [5]. In RUO laboratories, tesamorelin may be used as a receptor-directed probe to evaluate signaling relationships and endocrine feedback behavior under controlled experimental conditions.

Peripheral Nerve Biology & Growth Hormone Axis Augmentation (Preclinical Context)

The growth hormone axis has been discussed in preclinical literature as a modulator of cellular environments relevant to peripheral nerve injury models and regenerative biology research. Reviews have summarized potential mechanistic links between endocrine signaling and experimental outcomes in nerve repair paradigmsย [6]. These discussions support hypothesis generation for mechanistic studies (e.g., growth factor signaling, Schwann cell-associated pathways, and axonal outgrowth processes) in non-clinical settings.

Neuroendocrine Signaling & Biomarker Readouts in Cognitive Research

GHRH analogues have been evaluated in published research using biomarker and neurochemical readouts, including spectroscopy-associated measures and neurotransmitter-related endpoints, as part of broader investigations into neuroendocrine signaling in aging modelsย [7]. References are provided for pathway context only.

Figure included as an educational reference to the cited publication record.
Source:ย PubMed

Future Tesamorelin Research

Because tesamorelin is a well-characterized GHRH-pathway probe, ongoing research interest includes additional mechanistic mapping of GHRHR signaling kinetics, receptor desensitization, and endocrine feedback behavior in controlled experimental systems. Additional preclinical directions discussed in the literature include exploratory study designs that evaluate biomarker relationships in metabolic research and neuroendocrine signaling frameworks, as well as non-clinical investigations of endocrine influences on peripheral nerve biologyย [1]. Any mention of โ€œtrialsโ€ or โ€œapprovalโ€ in external sources is not an indication of intended use for this product; this material is supplied strictly for laboratory research.

This product is furnished exclusively for scientific research and educational purposes in controlled laboratory environments.

Resources

Clinical Review Report: Tesamorelin (Egrifta). Ottawa (ON): Canadian Agency for Drugs and Technologies in Health, 2016.

Mangili, J. Falutz, J.-C. Mamputu, M. Stepanians, and B. Hayward, โ€œPredictors of Treatment Response to Tesamorelin, a Growth Hormone-Releasing Factor Analog, in HIV-Infected Patients with Excess Abdominal Fat,โ€ PloS One, vol. 10, no. 10, p. e0140358, 2015. [PubMed]

Falutz et al., โ€œMetabolic effects of a growth hormone-releasing factor in patients with HIV,โ€ N. Engl. J. Med., vol. 357, no. 23, pp. 2359โ€“2370, Dec. 2007. [NEJM]

L. Stanley et al., โ€œReduction in visceral adiposity is associated with an improved metabolic profile in HIV-infected patients receiving tesamorelin,โ€ Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am., vol. 54, no. 11, pp. 1642โ€“1651, Jun. 2012. [PubMed]

Rochira and G. Guaraldi, โ€œGrowth hormone deficiency and human immunodeficiency virus,โ€ Best Pract. Res. Clin. Endocrinol. Metab., vol. 31, no. 1, pp. 91โ€“111, 2017. [PubMed]

H. Tuffaha et al., โ€œTherapeutic augmentation of the growth hormone axis to improve outcomes following peripheral nerve injury,โ€ Expert Opin. Ther. Targets, vol. 20, no. 10, pp. 1259โ€“1265, Oct. 2016. [PubMed]

D. Friedman et al., โ€œGrowth hormone-releasing hormone effects on brain ฮณ-aminobutyric acid levels in mild cognitive impairment and healthy aging,โ€ JAMA Neurol., vol. 70, no. 7, pp. 883โ€“890, Jul. 2013. [PubMed]

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATONAL AND EDUCATIONAL PURPOSES ONLY.

RUO Disclaimer

The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

For Laboratory Research Only. Not for human use, medical use, diagnostic use, or veterinary use.

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Storage Information

  • Store in a cool, dry environment

  • Protect from light and moisture

  • Keep vial tightly sealed when not in use

  • Handle using standard laboratory safety protocols

Tesamorelin 5mg $69.99

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